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Recommendations when to order or not order the test. May include related or preferred tests.
Acceptable panel to detect and subtype protein C and S deficiencies. Do not order if the individual has been on warfarin therapy in the previous 2-4 weeks.
New York DOH Approval Status
Indicates whether a test has been approved by the New York State Department of Health.
This test is New York state approved.
Specimen Required
Patient PreparationInstructions patient must follow before/during specimen collection.
CollectSpecimen type to collect. May include collection media, tubes, kits, etc.
Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.
Specimen PreparationInstructions for specimen prep before/after collection and prior to transport.
Transfer 4 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 2 mL)
Storage/Transport TemperaturePreferred temperatures for storage prior to and during shipping to ARUP. See Stability for additional info.
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Unacceptable ConditionsCommon conditions under which a specimen will be rejected.
Serum. EDTA plasma, clotted or hemolyzed specimens.
RemarksAdditional specimen collection, transport, or test submission information.
StabilityAcceptable times/temperatures for specimens. Times include storage and transport time to ARUP.
Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months, at -70°C: 6 months
Expected turnaround time for a result, beginning when ARUP has received the specimen.
1-5 days
Reference Interval
Normal range/expected value(s) for a specific disease state. May also include abnormal ranges.
Test Number
Components
Reference Interval
Protein C Functional
Age
Reference Interval (%)
1-4 days
17-53
5-29 days
20-64
30-89 days
21-65
90-179 days
28-80
180-364 days
37-81
1-6 years
40-92
7-9 years
70-142
10-11 years
68-143
12-13 years
66-162
14-15 years
69-170
16-17 years
70-171
18 years and older
83-168
Protein S Ag Free
Age
Male (%)
Female (%)
1-89 days
15-55
15-55
90-179 days
35-92
35-92
180-364 days
45-115
45-115
1-5 years
62-120
62-120
6-9 years
62-130
62-130
10-17 years
60-140
60-140
18 years and older
74-147
55-123
Interpretive Data
May include disease information, patient result explanation, recommendations, or details of testing.
Refer to report.
Compliance Category
FDA
Note
Additional information related to the test.
If Protein C Functional is low, Protein C, Total Antigen will be added. If Protein S Free is low, Protein S Total Antigen will be added. Additional charges apply.
Hotline History
N/A
CPT Codes
The American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
85303; 85306; if reflexed add 85302; if reflexed, add 85305
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Other names that describe the test. Synonyms.
Protein C, Functional and Protein S Free
Protein C, Functional with Reflex to Protein C, Total and Protein S, Free with Reflex to Protein S, Total
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